Ciprofloxacin is used in the treatment of various bacterial infections such as pharyngitis, tonsillitis, pneumonia, sinusitis, ear infections, urinary tract infections, genital tract infections, stomach infections, infections of bones and joints and skin and soft tissue infections. It can also be used in the management of patients with anthrax inhalation exposure.
Ciprofloxacin: Fluoroquinolone antibiotics
Ciprofloxacinworks by blocking the actions of certain bacterial proteins (such as DNA gyrase, topoisomerase IV) which is essential for the bacteria to survive. As a result, it destroys the susceptible bacteria and prevent their further growth and multiplication within the body which helps in reducing the severity of the infection.
Consult your doctor if you experience:
We have a range of different branded generic medicines available for ear infections, urinary tract infections, stomach (cephalex laugh line).
Our products are suitable for all ages with no special requirements like country or country of origin. So, us fellow doctors at for medical treatment and ongoing monitoring.
Ciprofloxacin usuallyis prescribed in the form of a a course of treatment 30 minutes before sexual activity. The recommended dose is 500 mg taken as a dose of 1 tablet. The duration of treatment is up to 4-6 hours. In some cases, the doctor may recommend discontinuing treatment “on line” or continuing the course of treatment in a specialist manner.
Do NOT take Ciprofloxacin if you are pregnant or breastfeeding unless prescribed by a doctor
Do NOT take this medication during the last 6 months of pregnancy unless stated otherwise.
In case of an allergic reaction called rashesContact your doctor immediately if any of these or these adverse effects occur.
Inform your doctor before taking this medicine if you have: severe liver problems such as severe jaundice (izophrenic) or other liver problems including a history of jaundice associated with Ciprofloxacin use
Severe kidney or liver problems including a history of kidney failure due to Ciprofloxacin use
Use of this medicine in the last 6 months of pregnancy is normally not required
Common side effects of Ciprofloxacin
The following side effects are common in the use of Ciprofloxacin:
New or worsening disease of your muscles, joints, or urinary tract? You must ask your doctor is pregnant or while using this medication before using it to ensure it is safe for you.Objective:To determine whether a single dose ciprofloxacin 500 mg once daily improves the outcome of ciprofloxacin-induced nephrotoxicity in patients with type 2 diabetes mellitus.
Materials and methods:Randomized controlled double-blind, placebo-controlled, double-blind study of the effects of a single dose of ciprofloxacin 500 mg once daily on the serum creatinine level and the plasma concentration of ciprofloxacin 500 mg on the serum levels of serum creatinine and on renal function.
Results:Ciprofloxacin 500 mg once daily produced more improvement in renal function than placebo. The mean change from baseline was 0.1 mm Hg for serum creatinine and 1.6 mm Hg for serum creatinine and the change from baseline was 0.4 mm Hg for serum creatinine and 1.0 mm Hg for the plasma concentration of ciprofloxacin.
Conclusions:Single dose ciprofloxacin 500 mg once daily is a safe and well-tolerated treatment for the treatment of type 2 diabetes mellitus.
Ciprofloxacin 500 mg once daily in the treatment of type 2 diabetes mellitusIntroduction:Chronic kidney disease is an important cause of morbidity and mortality worldwide. Ciprofloxacin is an effective agent in the treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The use of this drug in the treatment of acute kidney injury (AKI) and chronic kidney disease (CKD) can prevent the acute kidney injury (AKI) associated with diabetes mellitus, leading to the rechallenge of diabetic nephrons.
Aim:To determine whether single dose ciprofloxacin 500 mg once daily improves the outcome of ciprofloxacin-induced nephrotoxicity in patients with type 2 diabetes mellitus. The objective of this study is to determine whether single dose ciprofloxacin 500 mg once daily improves the outcome of ciprofloxacin-induced nephrotoxicity in patients with type 2 diabetes mellitus.
Methods:This was a double-blind, placebo-controlled, open-label, phase II clinical study, performed at the Department of Internal Medicine of the Faculty of Medicine, The University of Thessaly, Athens, Greece, from October 2016 to February 2019, in a multicenter, randomized, placebo-controlled, parallel-group, double-blind, placebo-controlled, double-blind, fixed-dose, placebo-controlled study.
During the study, a total of 2123 patients were randomized to receive ciprofloxacin 500 mg once daily for 10 days (study group). The mean change from baseline was 0.2 mm Hg for serum creatinine and 1.8 mm Hg for serum creatinine and the change from baseline was 0.7 mm Hg for serum creatinine and 1.0 mm Hg for the plasma concentration of ciprofloxacin. The mean change from baseline was 0.3 mm Hg for serum creatinine and 0.5 mm Hg for serum creatinine and the change from baseline was 1.3 mm Hg for serum creatinine and 1.0 mm Hg for the plasma concentration of ciprofloxacin.
The use of ciprofloxacin 500 mg once daily in patients with type 2 diabetes mellitus has been widely reported in studies and guidelines.
Dipyridamol, a non-steroidal anti-inflammatory drug (NSAID) is an effective and well-tolerated agent in the treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). Its use in the treatment of acute kidney injury (AKI) and chronic kidney disease (CKD) can prevent the acute kidney injury (AKI) associated with diabetes mellitus, leading to the rechallenge of diabetic nephrons.Cipro has been shown to cause some side effects. Talk to your health care provider if these mild reactions do not go away within a few days.
Common side effects reported from Cipro use include:
This is not a complete list of adverse reactions caused by Cipro.Call your doctor immediately if you experience the following:
Taking Cipro has been shown to impact your tendons (cords attaching bone to your muscles). It can increase your risk of developing tendonitis or a tendon rupture, especially if you’re over 60, taking steroid medications, or have a history of tendon problems.
Cipro can interact with other medications and substances, causing potentially serious side effects or allergic reactions. Tell your doctor if you are taking muscle relaxers such as tizanidine (Zanaflex), phosphodiesterase 5 (PDE5) inhibitors such as sildenafil, anticoagulants (blood thinners), antidepressants, antipsychotics, diuretics, insulin, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen.
This is not a complete list of Cipro drug interactions, so discuss any medications you’re on, even if you don’t see them listed here. Cipro can cause low blood sugar in some patients. Be wary of low blood pressure symptoms such as blurred vision, fatigue, confusion, pale skin, and cold sweats. Watch for these adverse effects if you have diabetes, and take diabetes medication orally. These could be signs of hypoglycemia and could lead to unconsciousness.
The U. S. Food and Drug Administration (FDA) has found that, while rare, fluoroquinolone antibiotics like Cipro can increase the occurrence of severe ruptures or tears in your aorta (a large artery that begins in the heart). These ruptures can lead to dangerous aortic bleeding, a heart attack, or even death, so people at risk for cardiac problems should be cautious about taking Cipro.
Be sure to tell your doctor if you have been diagnosed with or have a history of other medical conditions, including a prolonged QT interval (a rare heart problem that may cause an irregular heartbeat, fainting, or sudden death), aneurysms, kidney disease, liver disease, heart disease, myasthenia gravis (severe muscle weakness), seizures, or diabetes. Cipro can also significantly increase theophylline levels in your blood, leading to serious illness or death. This is not a comprehensive list of medical conditions that Cipro may affect, so speak with your doctor about your medical history before taking Cipro.
Cipro can cause your skin to become sensitive to sunlight or ultraviolet light, so try to avoid unnecessary sun exposure and do your best to wear protective clothing, sunglasses, or sunscreen that is SPF 15 or higher. Call your doctor if you notice redness, swelling, or blistering from sun exposure while on Cipro.
As with all prescription medication, inform the prescribing doctor about any medical conditions you have been diagnosed with and any medications or supplements you currently take before starting treatment. Antacids can reduce the amount of Cipro that your body absorbs, so be sure to take them at least 2 hours before or 6 hours after taking antacid medications.
In addition, let your doctor know if you are breastfeeding, pregnant, or planning on becoming pregnant before starting treatment with this medication.
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Ciprofloxacin HCl 1% Otic Solution, USP, is a broad-spectrum antibiotic that works to treat a wide range of bacterial infections in various body tissues. This antibiotic is commonly used to treat conditions like urinary tract infections, bronchitis, and other skin and soft tissue infections.
When a patient is taking a ciprofloxacin HCl 1% Otic Solution, the medicine will begin working within 30-60 minutes.
The first day of treatment with ciprofloxacin HCl 1% Otic Solution, the antibiotic is working fully in your body, with the exception of your skin and soft tissue, where it takes about 5-10 hours to start working. Ciprofloxacin HCl 1% Otic Solution takes only 1-2 days to start working in your body, and it is usually not necessary to use more than 1 dose a day.
Ciprofloxacin HCl 1% Otic Solution usually starts to work within 15-30 minutes, and it can be taken with or without food.
Ciprofloxacin HCl 1% Otic Solution usually remains in your system for around 2-3 days, however, it can be taken once or twice daily, as long as the patient is not pregnant or breastfeeding.
Ciprofloxacin HCl 1% Otic Solution usually stays in your system for around 3-5 days, but it can be taken once or twice daily, as long as the patient is not pregnant or breastfeeding.
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